What Dave said, but squirt some of the contact cleaner onto the RX pins for channel 2 as well. If the problem only happens on channel 2, it lets out a lot of the other stuff like power supplies since that has an effect on everything.
I've had pins go a bit wonky due to developing a dry joint in the RX, usually an old one that has seen a lot of swapping around. This needs the RX card digging out of its case to check the soldering on the underside.