On the assumption that you finished the model 2 years ago with enamel paints , the sanding sealer that you have applied is cellulose based and that will always attack an oil based enamel paint. There is no easy way around it but to rub down the whole thing and paint it again – I would suggest sticking to enamels. Enamel paint, e.g. Humbrol tinlets can be safely applied over Cellulose, but not the the other way round. I use Cellulose as a primer on a fibreglass hull and then paint with enamels. Some so called acrylic aerosol sprays can also atttack enamels.
If you want a good hardwearing finish to be applied over enamels, then Ronseal Clear Polyurethane Varnish (Gloss, Satin or Matt) will give a nice even hardwearing finish. This is oil based, not water based. Many DIY stores are promoting low odour water soluble varnishes now, so make sure you get the right one. I have finished all my models with this for many years with no problems.