Hi Bryan
I have entered into the brushless and Lipo world, but, with the help of club members!!!!
I have been luckily that the help was super great and saved me heaps of money!!!
The club mainly in the brushless and Lipo world use Hobbyking parts.
The ESC which sounds like your problem, we use the car ESC's with reverse from Hobbyking.
These are easy to program with their card.
The program card works on the HK 45 to 100 amp ones.
Also I have found that on the new gear, you TURN ON THE TRANSMITTER FIRST AND THEN THE RECEIVER.
To turn off TURN OFF THE RECEIVER(powers from the ESC) AND THEN TURN OFF THE TRANSMITTER.
Failure to do this upsets the ESC and the binding between the transmitter and receiver.
Also the throttle channel must be in the neutral position.
I screwed up one ESC so bad the only fix was using a servo manual test card to reset the dam thing!!!